The proteome is the set of proteins synthesized by an organism. The questions tackled by proteomics analyses include the identification of the proteins that are present in a sample, the analysis of their post-translational modifications, the analysis of quantitative variations between samples and the study of protein-protein interactions. Protemics analyses use and develop the tools that allow the study of complex mixtures of proteins to answer these questions.

The aim of the Plate-forme d'Analyse Protéomique de Paris Sud-Ouest (PAPPSO) is to provide research teams with equipments, skills and expertises in the field of proteomics, to allow them to respond to the most simple questions (identification of proteins from an organism the genome of which is entirely sequenced) as well as to complex questions (protein quantification in complex samples, dynamics of post-translational modifications,...) in the framework of collaborative projects and contracts..

PAPPSO arose by merging two complementary platforms. One of them is located in Jouy-en-Josas and is specialized in the analysis of prokaryotes, while the other is located in Gif-sur-Yvette (Le Moulon) and is specialized in plant biology. The complementarity of their expertise allows PAPPSO to propose different types of analysis, that are based either on protein or peptide separation or on shotgun techniques with or without isotopic labelling.

PAPPSO is open to national and international collaborations and has been labelled as such in 2009 (IbiSA label).

PAPPSO is endowed with a scientific committee.

PAPPSO thanks all the partners who have financially supported the platform.


	  irstea

	  CNRS